Acetone wrote:No, YOU have to be really clear about what YOUR saying. GM foods involves such a HUGE amount of different scientists and fields. Your saying ALL these fields have not yet settled their 'science'. (whatever that means)
When someone makes a claim that 'the science is unsettled' it's expected that they are talking about specifics.
First of all you intimate that you don't know what the term "settled science" means, then turn right around and and state an expectation you somehow think is applicable or relevant to a claim that "(a) science is unsettled."
But the term "unsettled science" can be rightfully used in a wide variety of contexts, some specific, some not so specific, some even quite general.
Acetone wrote:The is the same dishonest tactic that pops up so often in global warming threads. Oh these scientists don't agree about the extent of human impact. There's just so much for both sides that I don't know which is better!
I hope you're not accusing me of using dishonest tactics, because if you are I dare say you'll regret having done so. And besides, there's no real reason to assume or speculate that I am into using dishonest tactics in this discussion, and if you think there is, I'd like to see quotes of whatever I've said that led you to such a conclusion.
Acetone wrote:When really the scientists involved agree on nearly everything except for minor details and the overarching policy (which isn't a concern of science, but people tend to throw that in to the 'science unsettled' argument)
I don't care what others do, I'm not them.
In the GM foods arena we have to distinguish between the science that's involved and the fact that much of what goes on is technological in nature, and not scientific
per se. GM plants are
engineered, which makes them artifacts of a technological process, not simply a scientific process. The science is in plant biochemistry and physiology at the DNA level; the engineering is the design of gene splices in plant DNA.
Mistakes can be made in both facets, the science and the engineering; incomplete testing can lead to dangerous products.
Acetone wrote:So I want to know what you're talking about,
specifically.
It's difficult to be "specific" when the use of genetic engineering techniques in plant development involves such a wide variety of differing goals and approaches, as you certainly must be aware.
A number of genetically modified food materials and products have gained regulatory approval in the UK, Canada, and the US, and are in commercial use: cheese produced with genetically modified chymosin, tomato paste from slow softening tomatoes, and genetically modified soya and maize, among others. Other genetically modified food materials have cleared parts of the approval system (for example, clearance for food safety but awaiting environmental clearance for agricultural scale production).
These include oil from oilseed rape, starch and oil from maize, oil from cotton, chicory, a slow softening tomato intended to be eaten fresh, and riboflavin from a microbe. In addition, other products granted approval have not been developed to full commercial scale
... for example, I don't think genetically modified brewers' yeast and bakers’ yeast has been approved yet, although I'm not fully up on what's been approved and what hasn't been..
Most GM applications are for crop plants, and the genetic modifications are for commercially important agronomic traits
... mostly herbicide tolerance and insect resistance. These agronomic traits are determined by single genes and are therefore easiest to manipulate and the science involved is quite straightforward and well understood. In contrast, characteristics such as flavour, texture, and processing qualities tend to be determined by multiple genes and are much more difficult to manipulate with success.
Despite the technical difficulty, progress is and has been and continues to be made with genetically modifying the compositional and processing characteristics of food crops. For example, oilseed rape can now be modified to produce oils with wide ranging characteristics through selective modification of the length and degree of saturation of the fatty acids produced
... fatty acids such as laurate, typical of tropical vegetable oils, can now be produced in temperate oilseed crops. Similarly, the balance of sugar and starch in potatoes, which affects the processing quality of potatoes for snack food production (too much sugar produces a dark, poor tasting product), can also now be modified, but as yet to my knowledge only on an experimental scale.
In addition, genetic techniques are being used to identify and manipulate the genes for biologically active components of food crops, such as natural toxicants (for example, potato glycoalkaloids and kidney bean lectin), antinutrients (for example, trypsin inhibitors), and allergens (for example, certain nut proteins). Such developments are at early stages but in the longer term are almost certain to lead to the development of foods that lack these undesirable components, assuming things hold up.
For marketers, deterioration of fruits and vegetables is a huge problem, as I'm sure you are aware: the tendency of plant tissue to turn brown at a cut or peeled surface often has to be controlled through the use of preservatives such as sulphite. Damaged cells release the enzyme polyphenol oxidase, which catalyses the conversion of monophenols (released from separate subcellular compartments) to quinones, which oxidise to form brown polyphenolic pigments. However, the gene for polyphenol oxidase has been switched off in experimental studies by genetic modification, blocking this discolouration spoilage. Genetic modification and other molecular and biochemical techniques are being used to unravel the biochemistry of fruit and vegetable ripening and deterioration, and many new methods of preserving these foods, without the use of chemical preservatives, may be developed.
May be developed. This is an area of GMing plants that's nowhere settled technologically.
Another possibility is the use of crops to provide renewable sources of valuable materials such as vaccines, drugs, bioplastics, and other industrial materials. In parallel, cattle and sheep are being genetically modified to produce pharmaceutical chemicals in their milk, so that drugs can be produced much more efficiently and cost effectively. There is hope that food crops such as banana could be used to produce and deliver vaccines in tropical regions, for example.
This entails another area of GM wherein the technology has yet to become fully mature.
It is worth looking further at two other closely related concerns: the safety of genetically modified foods and the use of marker genes that confer antibiotic resistance. Environmental concerns are obviously important as well.
Food regulatoru agencies in the US, Canada and in the United Kingdom have led in developing systems for assessing the safety of genetically modified foods. Consequently, in these countries, genetically modified foods are subject to a rigorous safety assessment, based on rational scientific evaluation by leading experts and, by definition, within the limits of current knowledge. Within the European Union genetically modified foods are now regulated on a union-wide basis, and in the US and Canada they are regulated nationwide.
Widely reported work on potatoes at the Rowett Institute shows how difficult it can be to identify the facts Initial media reports claimed that the research proved that all genetically modified foods were inherently unsafe; subsequently it became clear that the findings related not to genetically modified potatoes at all but to
potato material to which concanavalin "A" (a lectin and known toxin) had been added. Obviosuly, this kind of situation emphasises the need to identify concerns precisely and assess claims critically.
Another case often cited as showing that genetically modified foods are inherently dangerous is that of the US company Pioneer Hi-Bred, which introduced genes from Brazil nuts into soybeans to increase the level of sulphur-rich amino acids. The soya was intended for animal feed, not human food. During tests it became clear that the nut protein that was transferred to soybean was allergenic to humans, and the company elected not to pursue the development, citing the potential difficulties of preventing the soya from entering the human food chain.
The use of antibiotic resistance as a marker system for gene uptake rightly continues to generate much concern. Again, it is important to identify and deal with specific concerns and not to condemn a general approach which has been invaluable in making genetic modification technically feasible. In general, the antibiotics used in marker systems are not used for treating diseases, and the gene and its product (that is, the enzyme that inactivates the antibiotic and thus confers resistance) would usually be destroyed during heat processing of the food material.
However, in two cases clinically important antibiotics have been used: a maize developed by Novartis contained a gene for ampicillin resistance, and a potato developed by Avebe contained a gene for amikacin resistance. A further complication with the maize is that the material was intended to be used unprocessed in animal feed and that the antibiotic resistance gene was under the control of a bacterial promoter.
That led to concerns that the antibiotic resistance gene might be transferred to animal gut flora (including human pathogens), which might then acquire resistance to a clinically useful antibiotic. As a consequence, both these genetically modified crops are having difficulties gaining full regulatory approval. In England, the Advisory Committee on Novel Foods and Processes and in the US, advisory committees to the US FDA have called for the development of different marker systems, and there's some evidence that alternative technologies are being developed. In the meantime it is imperative that the clinical use of antibiotics is not compromised.
There's an awfully lot of unsettled angles and facets in all of this, both in the science and in the technology. We could chose one and drill into its details and try to unravel the degree of uncertainty that it possesses, and if you want to "be specific" that's indeed what we'd have to do. I'm not so sure I'm up for that, being a rather busy guy and all. I'm satisfied that the science isn't entirely settled and the technologies aren't fully mature, which is all I need to know to avoid consuming GM foodstuffs (which is no mean feat but do-able and can be made routine) or using GM seeds.
What's revealed here is that the term "GM Foods" is much too general to offer any real utility in coming to grips with all that it means, all that it involves. This makes the very title of the thread almost meaningless.
As noted earlier in a different context, at my age it's hardly going to make a difference, but I have made my choices and I stick by them, just as you and otrhers can make your choices and stick by them too. This is why it's such a puzzle to me why some members here get all frothy at the mouth over this kind of thing and start shooting at one another like sombody was a criminal or something.
That just makes no sense to me and frankly, it's not something I'm used to encountering in science discussions in which I participate on the web. This forum seems to be particularly infected with contentious arguing and bickering and one-upsmanship games and spinmeistering that really don't have a place in discussions about science or scientific matters. Yet here, they seem to dominate. It's a mysery to me why they do, I must say.
But as I see it, these discussions are for the exchange of ideas and information and views and opinions to the end of informing participants to a greater degree than they'd otherwise be and thus serving to benefit the interests of all, and not intended to be a shooting gallery with involuntary targets.
Enjoy!