2019-nCoV or COVID-19

Serious discussion of the novel Corona Virus outbreak.

Understanding the basis and treatment of disease.

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Re: 2019-nCoV or COVID-19

#721  Postby kiore » Jun 07, 2020 9:18 pm

Blip wrote:I don't believe this has been posted here and the suggestion that coronavirus may be fundamentally a vascular disease seemed both interesting and credible. Do you have any comments, kiore? https://elemental.medium.com/coronavirus-may-be-a-blood-vessel-disease-which-explains-everything-2c4032481ab2


I do have comments the general gist of the article is what is becoming accepted among those studying and treating this illness, that is is not purely respiratory but has this extra vascular component. However part of the supporting science surrounding the ACE receptor studies is problematic Mandeep R. Mehra's study quoted has been retracted due to serious problems identified with the data set used and both the NEJM and the Lancet articles he recently primary authored have been retracted.
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Re: 2019-nCoV or COVID-19

#722  Postby newolder » Jun 07, 2020 9:33 pm

Happy caek day kiore. Nummy protein caek for all - dive in...

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Edit speloing :doh:
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Re: 2019-nCoV or COVID-19

#723  Postby kiore » Jun 07, 2020 9:49 pm

Thanks for the cake, it has been quite a year for me.
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Re: 2019-nCoV or COVID-19

#724  Postby Macdoc » Jun 07, 2020 9:56 pm

:cheers:
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Re: 2019-nCoV or COVID-19

#725  Postby The_Piper » Jun 07, 2020 10:36 pm

Happy birthday Kiore!
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pizza caek.jpeg (30.99 KiB) Viewed 1711 times

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As you might have guessed, I'm probably not going to NYC this year. Stay safe man. :cheers:
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Re: 2019-nCoV or COVID-19

#726  Postby newolder » Jun 08, 2020 6:11 pm

From Our World in Data:
Is the world making progress against the pandemic? We built the chart to answer this question

by Max Roser
June 08, 2020

Our World in Data presents the data and research to make progress against the world’s largest problems.
This blog post draws on data and research discussed in our entry on the Coronavirus Pandemic.

We update this chart – but not the text – daily
Reuse our work freely

...
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Re: 2019-nCoV or COVID-19

#727  Postby mingthething » Jun 10, 2020 7:48 am

Just a reminder that everyone is rushing to capitalize on COVID-19 to get published. It's sexy. It's the new pumpkin spice.
And when you overdo it with pumpkin spice, there will be the occasional rancid cookie and horrible-tasting coffee.
https://www.sciencemag.org/news/2020/06/whos-blame-these-thredroxntists-are-heart-surgisphere-covid-19-scandal?fbclid=IwAR3Z-1QC6b2dP9OLD14apYsG9YFUTy2gcS3kU3pCXp
Link gives a nice summary of the recent Surgisphere scandal. Among the rancid tell-tale signs? Patient recruitment and treatment with Hydroxychloroquine was given as early as 20th December 2019.
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Re: 2019-nCoV or COVID-19

#728  Postby kiore » Jun 11, 2020 3:59 am

mingthething wrote:Just a reminder that everyone is rushing to capitalize on COVID-19 to get published. It's sexy. It's the new pumpkin spice.
And when you overdo it with pumpkin spice, there will be the occasional rancid cookie and horrible-tasting coffee.
https://www.sciencemag.org/news/2020/06/whos-blame-these-thredroxntists-are-heart-surgisphere-covid-19-scandal?fbclid=IwAR3Z-1QC6b2dP9OLD14apYsG9YFUTy2gcS3kU3pCXp
Link gives a nice summary of the recent Surgisphere scandal. Among the rancid tell-tale signs? Patient recruitment and treatment with Hydroxychloroquine was given as early as 20th December 2019.


Yes it is unfortunate that reputable journals were so easily mislead here by Sapan Desai this has caused huge set backs in the knowledge base as many others were assuming this information was legitimate. It is not clear how much of this data is fraudulant and how widely this has contaminated real data.
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Re: 2019-nCoV or COVID-19

#729  Postby Alan B » Jun 15, 2020 12:00 pm

I get 404 on that link.
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Re: 2019-nCoV or COVID-19

#730  Postby NineBerry » Jun 15, 2020 12:43 pm

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Re: 2019-nCoV or COVID-19

#731  Postby Macdoc » Jun 15, 2020 8:48 pm

Pretty dire view from The Atlantic

The Virus Will Win
Americans are pretending that the pandemic is over. It certainly is not.
JUNE 12, 2020


https://www.theatlantic.com/ideas/archi ... in/612946/
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Re: 2019-nCoV or COVID-19

#732  Postby campermon » Jun 15, 2020 9:31 pm

I'm just watching the BBC news. We've got the highest covid deaths in the world and we know that the R value is near 1. Yet, in spite of this, people were crowding and shoving to get into JD Sports to buy a pair of trainers because the shops are open today.

Meanwhile, we're desperately working on how to get the kids back to school safely.

I feckin despair :nono:
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Re: 2019-nCoV or COVID-19

#733  Postby Macdoc » Jun 16, 2020 6:56 pm

This is very good news.

HEALTH NEWSJUNE 16, 2020 / 8:06 AM / UPDATED 27 MINUTES AGO
Steroid drug hailed as 'breakthrough' for seriously ill COVID-19 patients
Kate Kelland, Alistair Smout

LONDON (Reuters) - A cheap and widely-used steroid called dexamethasone has become the first drug shown to be able to save the lives of COVID-19 patients in what scientists said is a “major breakthrough” in the coronavirus pandemic.


https://www.reuters.com/article/us-heal ... SKBN23N1VP
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Re: 2019-nCoV or COVID-19

#734  Postby kiore » Jun 17, 2020 2:31 am

That steroids would help with lung inflamation in COVID-19 was predicted early on, but fell out of favour for a while this is good news it clearly back in the toolbox for those requiring ventilation and/or oxygen therapy. Not the golden bullet that is needed but the toolbox of symptomatic treatments is growing steadily. Also good news this is a cheap and commonly available item.
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Re: 2019-nCoV or COVID-19

#735  Postby Macdoc » Jun 17, 2020 2:41 am

Yeah partner was surprised it was not in the treatment protocol already but clearly given the fast approval there is some real benefit for those in serious trouble.
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Re: 2019-nCoV or COVID-19

#736  Postby minininja » Jun 17, 2020 1:31 pm

While obviously any effective treatments are good news, I do worry that the less responsible governments may take it as an excuse to say "see, we don't need to worry about preventing the spread anymore".
[Disclaimer - if this is comes across like I think I know what I'm talking about, I want to make it clear that I don't. I'm just trying to get my thoughts down]
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Re: 2019-nCoV or COVID-19

#737  Postby Macdoc » Jun 18, 2020 4:30 am

Good presentation ....


The old-school, the slow and the silver bullet: three options for a vaccine to free the world.

By Annika Blau, Ben Spraggon, Joshua Byrd and Catherine Hanrahan

Story Lab

Updated 17 Jun 2020, 20:20pm
Published 17 Jun 2020, 14:14pm
Dr Ross Jennens has devoted his career to saving lives — and now he’s on the coronavirus frontline.

But not in the way you might expect.

Dr Jennens has put his hand up, or rather his arm, and become one of the first people in the world to receive a vaccine that could protect him from coronavirus.

If it works, he’ll be able to treat his cancer patients at Epworth Hospital without worrying that he poses a risk to the very lives he’s trying to save.

But you don’t need to work in a hospital to be hanging out for a coronavirus vaccine. Without one, Australia could remain a hermit kingdom at the end of the Earth, cut off from the global community.

The world is in limbo and it’s unclear which, if any, of the more than 100 vaccine candidates might reach the finish line first.

Broadly speaking, there are three classes of vaccine and each has its own promises and drawbacks.

The old-school approach that can carry some risk.
The new-school approach that’s worked well before but still takes time we don’t have.
A silver bullet that’s cheap, could be produced quickly and could take us closer to a cure for cancer — but it’s never been used in humans before.
All three approaches have this in common: scientists are racing to solve the biggest problem in the world by tackling a microscopic one first..

more
https://www.abc.net.au/news/2020-06-18/ ... 10814?nw=0
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Re: 2019-nCoV or COVID-19

#738  Postby Alan B » Jun 20, 2020 11:10 am

NineBerry wrote:
Alan B wrote:I get 404 on that link.


https://www.sciencemag.org/news/2020/06 ... 19-scandal


Ouch! It seems 'Quackery' is taking on a new dimension...
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Re: 2019-nCoV or COVID-19

#739  Postby Alan B » Jun 20, 2020 11:50 am

kiore wrote:That steroids would help with lung inflamation in COVID-19 was predicted early on, but fell out of favour for a while this is good news it clearly back in the toolbox for those requiring ventilation and/or oxygen therapy. Not the golden bullet that is needed but the toolbox of symptomatic treatments is growing steadily. Also good news this is a cheap and commonly available item.

Yep. Excellent news. But what's the betting that some 'Big Pharma' freak will try to corner the market and put the price up?
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Re: 2019-nCoV or COVID-19

#740  Postby Macdoc » Jun 21, 2020 8:55 pm

not so excellent news

JUNE 21, 2020
One in four UK adults at risk of hunger and potential malnutrition following lockdown
by Northumbria University

Credit: CC0 Public Domain
One in four adults in the UK are experiencing food insecurity, which is likely to have left them susceptible to hunger and potential malnutrition, during the COVID-19 pandemic. That is the main finding of a survey published today by Feeding Britain and Northumbria University's Healthy Living Lab.

The survey finds that 25% of adults have struggled during the pandemic to access food they can afford, and are likely to have been susceptible to hunger and potential malnutrition as a result. Meanwhile, nearly one in four adults looking after children have eaten less so they can feed the children in their household.


https://medicalxpress.com/news/2020-06- ... ition.html
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