First 'three person baby' born using new method

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First 'three person baby' born using new method

#1  Postby DougC » Sep 28, 2016 12:03 am

http://www.bbc.co.uk/news/health-37485263

B.B.C. Article
The world's first baby has been born using a new "three person" fertility technique, New Scientist reveals.
The five-month-old boy has the usual DNA from his mum and dad, plus a tiny bit of genetic code from a donor.

Image
1) Eggs from a mother with damaged mitochondria and a donor with healthy mitochondria are collected
2) The majority of the genetic material is removed from both eggs
3) The mother's genetic material is inserted into the donor egg, which can be fertilised by sperm.


US doctors took the unprecedented step to ensure the baby boy would be free of a genetic condition that his Jordanian mother carries in her genes.
Experts say the move heralds a new era in medicine and could help other families with rare genetic conditions.
But they warn that rigorous checks of this new and controversial technology, called mitochondrial donation, are needed.
It's not the first time scientists have created babies that have DNA from three people - that breakthrough began in the late 1990s - but it is an entirely new and significant method.

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Re: First 'three person baby' born using new method

#2  Postby Rachel Bronwyn » Sep 28, 2016 12:22 am

So the fetus is, genetically, still the product of two people.
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Re: First 'three person baby' born using new method

#3  Postby pelfdaddy » Sep 28, 2016 2:36 am

Unless you happen to be writing inspired scripture, in which case the child came from the loins of the father, the mother being merely the vessel.
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Re: First 'three person baby' born using new method

#4  Postby Evolving » Sep 28, 2016 8:36 am

Rachel Bronwyn wrote:So the fetus is, genetically, still the product of two people.


Why do you say that? The nuclear DNA is from two people, the mitochondrial DNA from a third person.
How extremely stupid not to have thought of that - T.H. Huxley
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Re: First 'three person baby' born using new method

#5  Postby ScholasticSpastic » Sep 28, 2016 2:18 pm

I would jump in and pick nits, but I honestly have no idea how large or small a role mitochondrial DNA plays in determining human phenotypes.
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Re: First 'three person baby' born using new method

#6  Postby Rachel Bronwyn » Oct 03, 2016 11:13 pm

Me neither. It can certainly be responsible for disease though so it definitely contributes traits to some extent.

Evolving wrote:
Rachel Bronwyn wrote:So the fetus is, genetically, still the product of two people.


Why do you say that? The nuclear DNA is from two people, the mitochondrial DNA from a third person.


That's a good point as someone else is contributing the cytoplasm.
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