Nobel Prize winning drug works against malaria

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Nobel Prize winning drug works against malaria

#1  Postby kiore » Oct 28, 2015 1:12 am

This year the Nobel prize for medicine/physiology was shared by Youyou Tu, for her work on Artemisinin a component of the current successful treatment for malaria, and well deserved this was.
However this prize was shared with 2 others, Satoshi Ōmura and William C Campbell, who worked on the basis for the drug Ivermectin, a drug that also targets parasites, but instead of malaria their drug targeted river blindness and filariasis, and also is used against other parasites in human and veterinary medicine. Now it seems Ivermectin also works against malaria, both the carrier mosquitoes and the parasite itself.
http://www.bbc.com/news/health-34649016
What this all means? Well at some point it justifies significant more efforts to use Ivermectin as a general community based treatment in affected regions, to both eliminate the worm infections and to reduce the rate of malaria, as the article points out resistance to Ivermectin by mosquitoes is likely to follow however the purpose of such a campaign would be to reduce the incidence of malaria as a side effect of the deworming campaign, the artemether based drugs would still be first choice for treatment of malaria. The Malaria parasite would need to develop resistance to multiple forms of attack, in this case 3 separate anti-parasitics, the reduction of the mosquito population, even if only a short term effect would also keep the roll back malaria ball rolling.
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What does this stuff mean?
Read here:
general-science/folding-home-team-182116-t616.html
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