Wow...terminal breast cancer beat

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Wow...terminal breast cancer beat

#1  Postby Macdoc » Jun 04, 2018 7:18 pm

'Remarkable' therapy beats terminal breast cancer
By James Gallagher
Health and science correspondent, BBC News


https://www.bbc.com/news/health-44338276
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Re: Wow...terminal breast cancer beat

#2  Postby Alan B » Jun 05, 2018 11:30 am

Brilliant! Good news!

Now maybe there can be some similar Good News for prostate cancer which (it has recently been revealed) kills more men than breast cancer kills women...
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Re: Wow...terminal breast cancer beat

#3  Postby Scot Dutchy » Jun 05, 2018 11:57 am

She was lucky that it worked. With my girl friend it did not. One swallow....
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Re: Wow...terminal breast cancer beat

#4  Postby Macdoc » Jun 05, 2018 12:35 pm

It's not a matter of luck but of science moving treatments forward.....just as a recent at the time CHOPR addition benefitted me 10 years ago.

This is light years ahead as it is personalized immune system supercharging.....

A patient's immune system will already be attacking the tumour, it's just losing the fight between white blood cells and cancer.
The scientists screen the patient's white blood cells and extract those capable of attacking the cancer.
These are then grown in huge quantities in the laboratory.
Around 90 billion were injected back into the 49-year-old patient, alongside drugs to take the brakes off the immune system.


Lots of work to be done yet.... :coffee:
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Re: Wow...terminal breast cancer beat

#5  Postby Scot Dutchy » Jun 05, 2018 1:00 pm

Just piss off will you. My girlfriend had the exact same treatment. She was lucky and nothing else. It took. How many have failed.
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Re: Wow...terminal breast cancer beat

#6  Postby Fallible » Jun 05, 2018 2:12 pm

Yes, I think there is something like a 15% success rate.
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Re: Wow...terminal breast cancer beat

#7  Postby zulumoose » Jun 05, 2018 2:15 pm

One can only hope that the more they work with it the more successful and cheaper it will become, and hopefully they will at some stage be able to screen quickly which patients it will work for.
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Re: Wow...terminal breast cancer beat

#8  Postby Scot Dutchy » Jun 05, 2018 2:43 pm

Fallible wrote:Yes, I think there is something like a 15% success rate.


Which while giving a few a new life is hardly "WOW".
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Re: Wow...terminal breast cancer beat

#9  Postby felltoearth » Jun 07, 2018 11:24 am

My understanding about this is it focuses on the effectiveness of chemotherapy and outcomes weren’t significantly effected by its use in this particular form of breast cancer, and it seems genetic screening with individualized course of treatment seems more promising. As Macdoc says, more work to be done.
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Re: Wow...terminal breast cancer beat

#10  Postby Macdoc » Jun 08, 2018 1:56 pm

Individual medicine is
a) going to be hugely effective in a variety of conditions
b) going to be a huge hit on heathcare budgets..
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Re: Wow...terminal breast cancer beat

#11  Postby felltoearth » Jun 08, 2018 4:59 pm

Macdoc wrote:Individual medicine is
a) going to be hugely effective in a variety of conditions
b) going to be a huge hit on heathcare budgets..

In the grand scheme of things, paying for ineffective medicine is a hit on budgets as well, even if less expensive.
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Re: Wow...terminal breast cancer beat

#12  Postby Scot Dutchy » Jun 08, 2018 5:05 pm

Macdoc wrote:Individual medicine is
a) going to be hugely effective in a variety of conditions
b) going to be a huge hit on heathcare budgets..


Another load of bollocks? Stop equating everything to your self centred grotty little world.
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Re: Wow...terminal breast cancer beat

#13  Postby NNY » Jun 09, 2018 4:05 am

Alan B wrote:Brilliant! Good news!

Now maybe there can be some similar Good News for prostate cancer which (it has recently been revealed) kills more men than breast cancer kills women...

I had a friend send me a copy of the study, which answers the reason why they can't do it on prostate cancer yet.

Firstly, according the this NCBI study Somatic Mutations in Prostate Cancer: Closer to Personalized Medicine
The molecular cause of prostate cancer (PCa) is still unclear

So, because the cause of prostate cancer is still unclear, they wouldn't know what kind of T cell receptors, that would target the cancer, to create.

But because the cause of the terminal breast cancer the women had is known, they were able to create the appropriate T cells. The type of breast cancer she had was :
estrogen receptor (ER)-positive and ERB-B2 receptor tyrosine kinase 2 (ERBB2; also known as HER2)-negative metastatic breast cancer

It is only because they knew exactly the type of cancer she had that they were able to create the appropriate T cells for it. Also, according to the study, the type of cancer she had didn't mutate very much, but if the cancer was the type of cancer that mutated too much the T cells probably wouldn't have been able to kill all of the cancer.
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