and Is Converted to DNA: Study
Moderators: kiore, Blip, The_Metatron
The cell model that we used in this study is a carcinoma cell line, with active DNA replication which differs from non-dividing somatic cells. It has also been shown that Huh7 cells display significant different gene and protein expression including upregulated proteins involved in RNA metabolism
BNT162b2 suspension was then added in cell culture media to reach final concentrations of 0.5, 1.0, or 2.0 μg/mL. Huh7 cells were incubated with or without BNT162b2 for 6, 24, and 48 h. Cells were washed thoroughly with PBS and harvested by trypsinization and stored in −80 °C until further use.
Long interspersed nuclear element-1 (L1) retrotransposons are jumping genes that comprise 17% of human DNA. They utilize a ‘‘copy-and-paste’’ mechanism to propagate themselves throughout the genome via RNA intermediates, a process termed retrotransposition. L1s are active in the germ line and during embryogenesis, yet they are epigenetically suppressed in somatic cells. In cancer cells, however, L1s are aberrantly activated and may have a role in genome instability, one of the hallmarks of cancer pathogenesis.
The cell model that we used in this study is a carcinoma cell line, with active DNA replication which differs from non-dividing somatic cells. It has also been shown that Huh7 cells display significant different gene and protein expression including upregulated proteins involved in RNA metabolism [56]. However, cell proliferation is also active in several human tissues such as the bone marrow or basal layers of epithelia as well as during embryogenesis, and it is therefore necessary to examine the effect of BNT162b2 on genomic integrity under such conditions. Furthermore, effective retrotransposition of LINE-1 has also been reported in non-dividing and terminally differentiated cells, such as human neurons [57,58].
Pfizer’s COVID-19 Vaccine Goes Into Liver Cells
and Is Converted to DNA
The_Piper wrote::lol: This is way above my head but I'm happy there are others here who can ask critical questions. I saw a report of this study on CNN, but I'm still left with the question: "Does it matter?" I guess they're working on that now.
The Epoch Media Group's news sites and YouTube channels have spread conspiracy theories such as QAnon and anti-vaccine misinformation,[32] and false claims of election fraud in the 2020 United States presidential election.[36] In 2020, The New York Times called it a "global-scale misinformation machine".[27]
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