Posted: Jan 21, 2011 2:52 pm
The flagellum didn't evolve "by chance". It evolved by cumulative selection of functional (in the extant environment at the time) intermediates. This is clearly evidenced by the individual parts showing the expected (as in predicted) sequence homologies to each other, and functional paralogues in related non-flagellate structures in related organisms. Fuck, even the sequence of it's assembly is consistent with the evolutionary model.
Hey, remember where I told you about functional domains in proteins being reducible to patterns of polarity(the paper you keep ignoring), and that these domains are what evolution duplicates, mutates and shuffles, instead of the strawman caricature where evolution has to produce new entire folds one amino-acid at a time?
Well it turns out that not only do the individual parts in the flagellum which are postulated to be related, show the expected homologies to each other and their non-flagellate paralogues, but varations of the same functional folds are also found in these proteins in a sequence consistent with the evolutionary prediction.
Inb4 massive handwave and "it's all assumed to be true".
Hey, remember where I told you about functional domains in proteins being reducible to patterns of polarity(the paper you keep ignoring), and that these domains are what evolution duplicates, mutates and shuffles, instead of the strawman caricature where evolution has to produce new entire folds one amino-acid at a time?
Well it turns out that not only do the individual parts in the flagellum which are postulated to be related, show the expected homologies to each other and their non-flagellate paralogues, but varations of the same functional folds are also found in these proteins in a sequence consistent with the evolutionary prediction.
Inb4 massive handwave and "it's all assumed to be true".