Posted: Jun 09, 2012 11:37 pm
Hepatocytes typically store fat or glycogen in their vacuoles. If the disease is as you described, I would guess glycogen would be in the vacuole.
The fibrotic changes (in humans anyway) come from excess fat getting stored in the vacuoles (Non-alcholic steatotic hepatitis) and this causes thickening of the connective tissues that provide the scaffold for the hepatocytes, blood vessels, and bile ducts, thus distorting the livers 'architecture'.
The fibrotic changes (in humans anyway) come from excess fat getting stored in the vacuoles (Non-alcholic steatotic hepatitis) and this causes thickening of the connective tissues that provide the scaffold for the hepatocytes, blood vessels, and bile ducts, thus distorting the livers 'architecture'.