Posted: Oct 11, 2021 2:17 am
by kiore
Stagman wrote:
Cito di Pense wrote:
I'm a happy recipient of two doses of Moderna, four months down the line from my second. I don't post much any more, but I'm as hale and hearty (and dour) as I was before "the dose".

Out of curiosity, do you know if your antibody levels are sufficient? I am 5 months after my second Moderna dose, yet the IgG SARS-CoV-2 antibodies have since subsided to below what is accepted as sufficient. I might add I am immune suppressed.


Ab's are not the entire immune system, but I think it now fairly well recognized that some groups should have a 3rd dose of the MRNA vaccines. The Moderna (Spikevax) vaccine tends to have more persistence than the competition, whether this due to its higher base dose or the 2nd dose spacing or both or something else.. If you are already after only 5 months showing low levels of Abs, (by the way I am yet to be convinced that it totally clear what the needed levels are) then you should seek advice regarding getting a 3rd dose in your location.
Moderna is seeking approval in the USA for a reduced dose for the 3rd dose (50mcg), but here those at high risk have been received 3rd doses at the same 100mcg dose at the initial rounds.
I recently was offered and received my 3rd dose of Moderna 100mcg after 8 months due to being in a high risk group with no history of native infection and was happy to get it. In other places 3rd doses are starting to happen for some groups and even as a mix and match with 2 different vaccine types. It remains to be seen whether mixing types or continuing course prove better long-term.