Posted: Jun 14, 2012 8:14 am
DavidMcC wrote:CharlieM wrote:“Cancer is no more a disease of cells than a traffic jam is a disease of cars
BS! Cancer is essentially a failure of the cell to respond to apoptosis signals, like FADD. Phosphorylation of FADD causes it to fail to precipitate cell death, leading to uncontrolled cell division and growth, ie, cancer.
http://www.nature.com/bjc/journal/v94/n4/full/6602955a.html
Um, partly but not quite. That is just one of the hallmarks of cancer, and cells need to exhibit all of them to qualify as cancerous. (See Hanahan and Weinberg, The Hallmarks of Cancer).
http://www.cell.com/abstract/S0092-8674%2811%2900127-9