Unraveling the connections of the brain

Chromatin regulators in neuronal connectivity

Studies of mental functions, behaviors and the nervous system.

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Unraveling the connections of the brain

#1  Postby kennyc » Jul 19, 2014 12:05 pm


The brain is complex, heck if it wasn’t then we wouldn’t be smart enough to figure out how it works. I guess it’s one of those stupid catch-22 type things. Still, little is known about how the brain forms connections and the process that is behind all that. Thankfully new research provides an important glimpse into the processes that establish connections between nerve cells in the brain. These connections [also known as synapses] allow nerve cells to transmit and process information involved in thinking and moving the body. Sounds simple enough, but the formation is quite complex.

The finding is, of course, an important step forward in efforts to learn how the developing brain is built. This is an area of research essential to understanding the causes of things like intellectual disability and autism, or even cooler growing actual brains.....
The new results show that a complex of proteins known as NuRD [ the short term for nucleosome remodeling and deacetylase] plays a fairly high supervisory role in some aspects of the cerebellum’s construction. When the researchers blocked the NuRD complex, cells in the cerebellum called granule cells failed to form connections with other nerve cells, the Purkinje neurons [named after the guy who discovered them, hence the weird sounding name]. These circuits are important for the cerebellum’s control of movement coordination and learning.


Journal reference: http://www.cell.com/neuron/abstract/S0896-6273(14)00483-8
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Re: Unraveling the connections of the brain

#2  Postby Keep It Real » Jul 19, 2014 5:59 pm

No mention of "quantum fluctuations" - I'm surprised you find this intellectually nourishing kennyc.
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