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Federico wrote:I don't have access to the paper you mention in your post, however, I have read, and partially reproduce here, the abstracts of two of your papers which -- if I am not badly mistaken -- support my opinions.
Mr.Samsa wrote: You are badly mistaken. Douglas, the author of the paper, has explained how you have misunderstood the findings of his papers. I can understand you refusing to believe me when I tell you that you've misunderstood the papers you've been presenting, but now you have the actual author of the paper telling you that you are mistaken. Surely that causes you at least a moment's hesitation?
Federico wrote:Mr.Samsa wrote: You are badly mistaken. Douglas, the author of the paper, has explained how you have misunderstood the findings of his papers. I can understand you refusing to believe me when I tell you that you've misunderstood the papers you've been presenting, but now you have the actual author of the paper telling you that you are mistaken. Surely that causes you at least a moment's hesitation?
I really find it impossible to follow you. At the beginning of our discussion you were writing Epigenetics had no role to play in the effects of the environment on the genome.
Federico wrote:But now you accept that stress can change the phenotype of the fetus through the epigenome, and even add Douglas has explained how wrong I was in basically saying the same thing.
Back to the violin playing parents, unless this is very stressful (which it appears to be in Tiger Mom's home!), it is unlikely that the kids will inherit this trait. If it is stressful (the child could not eat nor use the restroom until the piece was perfect!) then the tortured violinist's children could be epigenetically disrupted. I suppose that rare epigenetic disruptions could affect behavior, such as violin playing, but it would be very rare and would have to be selected.
Federico wrote:Actually, you are saying no matter what kind of environmental change the fetus is exposed to through the mother(diet, smoke, toxic agents, divorce, war, etc), the effects will be the same on the fetus because the mechanism (stress) is the same in every case. Something Douglas didn't say.
Federico wrote:And then, you bring back the violin which is just an epiphenomenon.
Federico wrote:I have written myself very clearly it's aptitude for music which is innate and probably the result of a combination of Darwinian and quasi-Lamarckian mechanisms of transmission. And, furthermore, I believed ludicrous the idea that without any musical aptitude (or Talent) anyone could become a Paganini just by picking up a Stradivarius and fiddling long enough.
Federico wrote:And now you want me to accept that ".... people won't activate genes that make them better violinists, and basketballers, and more religious, or whatever. Instead the change is simply a reaction to the stress, which is constant across all those situations,"
, which doesn't make sense. IMO, psychological stress may modify the sex orientation of the fetus by a mechanism which will be different from that observed under nutritional stress.
Federico wrote:In any case, I'm waiting for Douglas response to my post which, hopefully, will settle our differences, otherwise lets agree to disagree.
Mr.Samsa wrote:
Seriously Federico - if you misrepresent me one more time, I'm going to report you.
Zwaarddijk wrote:Federico,
misrepresenting someone is against the FUA, and you keep putting words in other people's mouths here.
Someone wrote:There's a whole other world out there. Algeria just opened up after 19 years yesterday, and it's blah-blah like you really should care about how this thread settles matters. It won't. This is not a science journal, and interpretations here are non-authoritative ones.
Someone wrote:There's a whole other world out there. Algeria just opened up after 19 years yesterday, and it's blah-blah like you really should care about how this thread settles matters. It won't. This is not a science journal, and interpretations here are non-authoritative ones.
Federico wrote:Someone wrote:There's a whole other world out there. Algeria just opened up after 19 years yesterday, and it's blah-blah like you really should care about how this thread settles matters. It won't. This is not a science journal, and interpretations here are non-authoritative ones.
I agree 1000% about both counts.
However, lets not forget we have a Science and the Humanities section to which contribute a fair number of scientifically competent members of RS, as well as a Competition for the best scientific essay.
Having written that, I also agree with you many members of RS may not have a scientific background but may be interested in the topic being discussed, thus the importance not to become too abstruse.
If you give a peek at some of my threads (The Cognitive Mind; Genetic markers in Jewish people; etc, you'll find I strived to accomplish that, unless forced to but failed to provide more detailed proof evidence.
Federico wrote:Mr.Samsa wrote:
Seriously Federico - if you misrepresent me one more time, I'm going to report you.
Mr. Samsa,
You know the expression "You can't beat City Hall". So, go ahead and report me, and to make your task easier, I'll even suggest two good reasons for reporting me: 1) For steadfastly sustaining my opinions, and 2) For insubordination.
Federico wrote:In the meanwhile, I have summarized your comments on my opinions about why (e.g.) some people are born with an innate talent for music while others are not, and about the respective roles of the genome, the Epigenome, and the Environment.
Federico wrote:*snip*
Federico wrote:For quite a while I really thought you and me were talking in two different languages which explained the difficulties in understanding each other. Then, finally, it dawned on me: "We were indeed speaking different languages. I was speaking in Chemicalese and you in Behavioralese. The same words like epigenetic and environment had entirely different meaning depending on which language one used. Example:
Eriksson’s psychosocial development theory
Eriksson believed that his psychosocial principle is genetically inevitable in shaping human development. It occurs in all people.
He also referred to his theory as 'epigenesis' and the 'epigenetic principle', which signified the concept's relevance to evolution (past and future) and genetics.
Eriksson explained his use of the word 'epigenesis' thus: "...epi can mean 'above' in space as well as 'before' in time, and in connection with genesis can well represent the space-time nature of all development..." (from Vital Involvement in Old Age, 1989).
In Eriksson’s theory, Epigenetic therefore does not refer to individual genetic make-up and its influence on individual development.
Psychological Theories
A summary of psychological theories focusing on environmental versus epigenetic theories.
Federico wrote:Mr. Samsa, you should have told me before. Actually you gave me a few hints, but it takes more for waking me up.
But, in the end, it makes everything much easier: No reason to fight because we just have read two different books on human development and, as they say, "The twain shall never meet."
Mr.Samsa wrote:
What is so hard about understanding my position? I literally spelt it out to you in the largest font size available on this forum, in bold, multiple times. Yet you continue to make ridiculous claims about what you think I've said. Initially I assumed it was an inability to understand what I was saying, but given how many times I've clarified, explained, and summarised my position for you, I can only assume that further misrepresentation is done purposely.
One last time, I will try to explain it in extremely simple terms so hopefully you'll understand.
Epigenetic environment: These are things in the physical location that can cause chemical changes, like stress, cigarettes, alcohol, drugs, etc.
Learning environment: These are things which like culture, experience, and so on, like playing the violin, basketball, etc. Unless the violin or basketball is made of radioactive material, these activities will not change the genome.
Well if you've only read a single book on the subject then that explains why you know fuck all about epigenetics. Try reading some more books, .
Federico wrote:Very well, Mr.Samsa, I give up. I must be a moron because I still think that, mechanistically, the two are the same.
But enough discussions and, please, give me the names of the books you believe I should read to learn something about epigenetics. I promise I'll read them all.
Indeed, what I have read up to now on the subject can be found in these books which, obviously, are not sufficient:
[*]Molecular Biology of the Cell - Fifth Edition, by Bruce Alberts et al.
[*]Molecular Biology of the Gene, Sixth Edition, by James D.Watson et al.
[*]Recombinant DNA: Genes and Genomes - A Short Course, Third Edition , by James D.Watson et al.
Mr.Samsa wrote:
Basically, you need to realize that your current understanding of epigenetics is woefully and painfully wrong......
......There is nothing about playing a violin that will change your genetics to make you better at playing the violin. Full stop. If you think there is, then you are wrong - there is no debate that can take place on this point as it is undeniably, absolutely, wholly and completely wrong. You will never find an article or researcher who would support that claim.
Accept this and move on.
Shrunk wrote:
I think the vehement reaction that Pinker's "cheescake" comment has often elicited is not justified. Some of the greatest achievements of humankind, (Bernini's cathedrals, Shakespeare's tragedies, and Michelangelo's scuptures no less than Beethoven's symphonies) could aptly be called "cheesecake". The creation and consumption of cheesecake, in all its guises, is what makes us human.
Federico wrote:Well Mr.Samsa,
our problem was and remains one of misunderstanding, not misrepresenting.
Federico wrote:In any case, I'll reproduce what I wrote just a few posts back, which summarizes pretty well my hypothesis about the origin of musical talent and its heritability.
If you believe it's pure BS, I'll accept your verdict and also your advice to move on to other topics.
Federico » Feb 15, 2011
……..it can be hypothesized that aptitude for music can be inherited through the combined effects of genomic and epigenomic mechanisms. The first one would have occurred several millions of years ago, and consisted in a random mutation in a gene (or genes) resulting in the development of musical talent (probably for singing, initially), which would have given the holder of the mutation and his descendants an evolutionary advantage.
Federico wrote:In more recent, historical times, some favorable changes in the living environment of some tribes (long period of peace, great abundance of food, etc) may have resulted in free time for singing, dancing, and making some rudimentary musical instruments.
These novel activities, which partly replaced hunting and gathering, would result in modifications of the epigenomic control of genes which could be transmitted to the next generations.
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